Markey Cancer Center Biospecimen and Tissue Procurement Shared Resource Facility, United States

Registration Status: Completed

Objective: The Markey BSTP SRF collects, processes, annotates, stores and distributes biospecimens to support translational research in cancer and other diseases. Markey BSTP SRF support includes obtaining IRB certification, collecting Informed Consents or the acquisition and the processing of targeted biospecimens in accordance with specific research protocols. Our services are available to University of Kentucky (UK) faculty and other qualified investigators in partnership with UK faculty.

Registered Biobank Name	Markey Cancer Center Biospecimen and Tissue Procurement Shared Resource Facility
Biobank Leader	Brent J. Hallahan, PhD
Country	United States
Email for biobank inquiries	bhallahan@uky.edu
Principal Investigator	C. Darrell Jennings, MD
Website	http://ukhealthcare.uky.edu/markey/biospecimen/
User Type Mono: A biobank that supports a specific research project, may have few staff members, a small-scale accrual scope with little to no initial intention of releasing or distributing biospecimens to secondary parties Oligo: A biobank that supports several research groups or clinical trials, may or may not be designed to release biospecimens outside their collaborative group Poly: A biobank that has generally a larger accrual scope, resources, and multiple users outside the biobank proper	Poly - Collection aimed at supporting undetermined, multiple users with ethics approved research projects, through a defined access/application mechanism.

Biospecimen Collected:

Cohort Highlights

100 cases Next Generation Sequencing assay to detect all classes of genetic variant in Lung Cancer using a single Diagnostic test.
200 cases Colorectal TMA for QC purposes in support of study of tumor infiltrating lymphocytes in ovarian cancer tissues.
Build 300 cases breast cancer TMA containing primary tumour and matched metastatic LN for various subtypes (luminal, HER2, Triple negative). Start with Triple negatives.
125 cases Breast tumour and metastatic lymph nodes in breast cancer cases with outcomes of metastasis to lung or bone.
100 cases of rare tumours - fibrolamellar hepatocellular carcinoma. FFPE, frozen, BC.
200 cases of FFPE tissue sections from breast, lung adenocarcinoma, and lung squamous cell carcinoma with matching normal tissue (only pathology data requested).