Ontario Veterinary College Veterinary Biobank, Guelph, Canada

Certification Status: Complete Education

Registration Status: Completed

Objective: Located at the University of Guelph, the Institute for Comparative Cancer Investigation (ICCI) manages a unique biobank: the Ontario Veterinary College Veterinary Biobank (OVCVB). OVCVB is a biorepository of specimens primarily from naturally occurring cancers in companion animals (dogs and cats), however the scope of the biobank is expanding to include other diseases and areas of interest. The most prevalent types of cancers in the CATSB are: hemangiosarcoma, osteosarcoma, mast cell tumours, lymphoma and soft tissue sarcoma. With client consent, samples are collected from patients of the Ontario Veterinary College Health Sciences Centre and the Mona Campbell Centre for Animal Cancer. The OVCVB is a unique resource with the mission to facilitate basic, comparative, and translational research and complement preclinical rodent studies, thereby advancing the understanding of disease and improving treatment options to benefit both companion animal and human patients.

Registered Biobank Name	Ontario Veterinary College Veterinary Biobank, Guelph
Biobank Leader	Deirdre Stuart
Country	Canada
Email for biobank inquiries	tumbank@uoguelph.ca
Principal Investigator	Drs Geoff Wood and Michelle Oblak
Website	https://icci.uoguelph.ca/ovc-veterinary-biobank/
User Type Mono: A biobank that supports a specific research project, may have few staff members, a small-scale accrual scope with little to no initial intention of releasing or distributing biospecimens to secondary parties Oligo: A biobank that supports several research groups or clinical trials, may or may not be designed to release biospecimens outside their collaborative group Poly: A biobank that has generally a larger accrual scope, resources, and multiple users outside the biobank proper	Poly - Collection aimed at supporting undetermined, multiple users with ethics approved research projects, through a defined access/application mechanism.

Biospecimen Collected:

Cohort Highlights

100 cases Next Generation Sequencing assay to detect all classes of genetic variant in Lung Cancer using a single Diagnostic test.
200 cases Colorectal TMA for QC purposes in support of study of tumor infiltrating lymphocytes in ovarian cancer tissues.
Build 300 cases breast cancer TMA containing primary tumour and matched metastatic LN for various subtypes (luminal, HER2, Triple negative). Start with Triple negatives.
125 cases Breast tumour and metastatic lymph nodes in breast cancer cases with outcomes of metastasis to lung or bone.
100 cases of rare tumours - fibrolamellar hepatocellular carcinoma. FFPE, frozen, BC.
200 cases of FFPE tissue sections from breast, lung adenocarcinoma, and lung squamous cell carcinoma with matching normal tissue (only pathology data requested).