Brain tumor cell resource, Canada

Registration Status: Completed

Objective: The objective of this brain tumor cell resource is to develop a repository of brain tumor cells derived from brain tumor patient tissues obtain during surgery. The brain tumor cell resource is intended to support research into brain tumors. While the main focus is on adult glioblastoma, we also collect and isolate tumor cells from other brain tumors, with astrocytomas, meningiomas and oligodendrogliomas forming the bulk of other brain tumors collected.

Registered Biobank Name	Brain tumor cell resource
Biobank Leader	Marshall Pitz, Sabine Hombach-Klonisch
Country	Canada
Email for biobank inquiries	thomas.klonisch@umanitoba.ca
Principal Investigator	Thomas Klonisch
Website
User Type Mono: A biobank that supports a specific research project, may have few staff members, a small-scale accrual scope with little to no initial intention of releasing or distributing biospecimens to secondary parties Oligo: A biobank that supports several research groups or clinical trials, may or may not be designed to release biospecimens outside their collaborative group Poly: A biobank that has generally a larger accrual scope, resources, and multiple users outside the biobank proper	Oligo - Collection aimed at supporting several research projects, a research group or a research consortium

Biospecimen Collected:

Cohort Highlights

100 cases Next Generation Sequencing assay to detect all classes of genetic variant in Lung Cancer using a single Diagnostic test.
200 cases Colorectal TMA for QC purposes in support of study of tumor infiltrating lymphocytes in ovarian cancer tissues.
Build 300 cases breast cancer TMA containing primary tumour and matched metastatic LN for various subtypes (luminal, HER2, Triple negative). Start with Triple negatives.
125 cases Breast tumour and metastatic lymph nodes in breast cancer cases with outcomes of metastasis to lung or bone.
100 cases of rare tumours - fibrolamellar hepatocellular carcinoma. FFPE, frozen, BC.
200 cases of FFPE tissue sections from breast, lung adenocarcinoma, and lung squamous cell carcinoma with matching normal tissue (only pathology data requested).