OMiCS - Optimizing Movement in Children Study, Canada

Registration Status: Completed

Objective: With the Optimizing Movement in Children Study (OMiCS) we investigate the effects of physical activity on the proteome, metabolome, and microbiome in 8-10 year old children of varying physical activity levels. For this cross-sectional study, children's physical activity levels are assessed with accelerometers. Traditional health measures include: anthropometrics (height, weight, waist circumference), spirometry, resting heart rate and blood pressure. Furthermore, we assess cortisol levels in hair, and telomere length. Other assessed measures include: sleep, sedentary time, and socioemotional health assessments as they pertain to physical activity. Blood serum, plasma, and mRNA are biobanked for this study.

Registered Biobank Name	OMiCS - Optimizing Movement in Children Study
Biobank Leader	Sarah Koch
Country	Canada
Email for biobank inquiries	sarahkoch@alumni.ubc.ca
Principal Investigator	Dr. Eli Puterman
Website
User Type Mono: A biobank that supports a specific research project, may have few staff members, a small-scale accrual scope with little to no initial intention of releasing or distributing biospecimens to secondary parties Oligo: A biobank that supports several research groups or clinical trials, may or may not be designed to release biospecimens outside their collaborative group Poly: A biobank that has generally a larger accrual scope, resources, and multiple users outside the biobank proper

Biospecimen Collected:

Cohort Highlights

100 cases Next Generation Sequencing assay to detect all classes of genetic variant in Lung Cancer using a single Diagnostic test.
200 cases Colorectal TMA for QC purposes in support of study of tumor infiltrating lymphocytes in ovarian cancer tissues.
Build 300 cases breast cancer TMA containing primary tumour and matched metastatic LN for various subtypes (luminal, HER2, Triple negative). Start with Triple negatives.
125 cases Breast tumour and metastatic lymph nodes in breast cancer cases with outcomes of metastasis to lung or bone.
100 cases of rare tumours - fibrolamellar hepatocellular carcinoma. FFPE, frozen, BC.
200 cases of FFPE tissue sections from breast, lung adenocarcinoma, and lung squamous cell carcinoma with matching normal tissue (only pathology data requested).