Nicklaus Children's Hospital Biobank, United States

Registration Status: Pending

Objective: Nicklaus Childrenâ€™s Hospital Biobank collects samples and health information from volunteers, regardless of health history. Eligible donors of biospecimens include children and adults at participating clinical sites and community events. Supports research, development of therapies and to expand our understanding about health and disease that acknowledge the genetic diversity of our community. The goal is to increase the diversity of populations under-represented in biomedical research.

Registered Biobank Name	Nicklaus Children's Hospital Biobank
Biobank Leader	Paula Espinal
Country	United States
Email for biobank inquiries	paula.espinal@nicklaushealth.org
Principal Investigator	Steve Melnick
Website
User Type Mono: A biobank that supports a specific research project, may have few staff members, a small-scale accrual scope with little to no initial intention of releasing or distributing biospecimens to secondary parties Oligo: A biobank that supports several research groups or clinical trials, may or may not be designed to release biospecimens outside their collaborative group Poly: A biobank that has generally a larger accrual scope, resources, and multiple users outside the biobank proper

Biospecimen Collected:

Cohort Highlights

100 cases Next Generation Sequencing assay to detect all classes of genetic variant in Lung Cancer using a single Diagnostic test.
200 cases Colorectal TMA for QC purposes in support of study of tumor infiltrating lymphocytes in ovarian cancer tissues.
Build 300 cases breast cancer TMA containing primary tumour and matched metastatic LN for various subtypes (luminal, HER2, Triple negative). Start with Triple negatives.
125 cases Breast tumour and metastatic lymph nodes in breast cancer cases with outcomes of metastasis to lung or bone.
100 cases of rare tumours - fibrolamellar hepatocellular carcinoma. FFPE, frozen, BC.
200 cases of FFPE tissue sections from breast, lung adenocarcinoma, and lung squamous cell carcinoma with matching normal tissue (only pathology data requested).