CHTN VUMC, Canada

Registration Status: Pending

Objective: VUMC-CHTN is primarily funded by the National Cancer Institute as a human surgical and autopsy remnant tissue procurement facility. Federal funds support less than 25% of operational costs with the other 75% of costs being recouped via services. The biorepository operates under a waiver of consent and also consents participants for use of remnant tissue and biofluid collection. Academic and commercial investigators with R&D protocols are encouraged to apply. We are not subsidized to support clinical trials.

Registered Biobank Name	CHTN VUMC
Biobank Leader	Kerry Wiles
Country	Canada
Email for biobank inquiries	kerry.wiles@vumc.org
Principal Investigator	Dr. Mary Kay Washington
Website
User Type Mono: A biobank that supports a specific research project, may have few staff members, a small-scale accrual scope with little to no initial intention of releasing or distributing biospecimens to secondary parties Oligo: A biobank that supports several research groups or clinical trials, may or may not be designed to release biospecimens outside their collaborative group Poly: A biobank that has generally a larger accrual scope, resources, and multiple users outside the biobank proper

Biospecimen Collected:

Cohort Highlights

100 cases Next Generation Sequencing assay to detect all classes of genetic variant in Lung Cancer using a single Diagnostic test.
200 cases Colorectal TMA for QC purposes in support of study of tumor infiltrating lymphocytes in ovarian cancer tissues.
Build 300 cases breast cancer TMA containing primary tumour and matched metastatic LN for various subtypes (luminal, HER2, Triple negative). Start with Triple negatives.
125 cases Breast tumour and metastatic lymph nodes in breast cancer cases with outcomes of metastasis to lung or bone.
100 cases of rare tumours - fibrolamellar hepatocellular carcinoma. FFPE, frozen, BC.
200 cases of FFPE tissue sections from breast, lung adenocarcinoma, and lung squamous cell carcinoma with matching normal tissue (only pathology data requested).