CANPREV, Canada

Certification Status: Complete Education

Registration Status: Completed

Objective: The goal is to develop a Transplant Biobank for the collection, storage and use of biological specimens from patients undergoing solid organ, stem cell and tissue transplantation. It will fuel translational research in this field and will improve patient outcomes in BC, in Canada and worldwide. The project will build on the foundation created by Genome Canada, and will house the almost 10,000 specimens from donors and recipients of kidney, heart, liver, lung pancreas and bone marrow transplants currently in the Immunology Laboratory. It will create the leading source for biological transplant samples in Canada, and one of the most important such resources in the world.

Registered Biobank Name	CANPREV
Biobank Leader	Karen Sherwood
Country	Canada
Email for biobank inquiries	biorepository@vch.ca
Principal Investigator	Paul Keown / Karen Sherwood
Website
User Type Mono: A biobank that supports a specific research project, may have few staff members, a small-scale accrual scope with little to no initial intention of releasing or distributing biospecimens to secondary parties Oligo: A biobank that supports several research groups or clinical trials, may or may not be designed to release biospecimens outside their collaborative group Poly: A biobank that has generally a larger accrual scope, resources, and multiple users outside the biobank proper	Poly - Collection aimed at supporting undetermined, multiple users with ethics approved research projects, through a defined access/application mechanism.

Biospecimen Collected:

Cohort Highlights

100 cases Next Generation Sequencing assay to detect all classes of genetic variant in Lung Cancer using a single Diagnostic test.
200 cases Colorectal TMA for QC purposes in support of study of tumor infiltrating lymphocytes in ovarian cancer tissues.
Build 300 cases breast cancer TMA containing primary tumour and matched metastatic LN for various subtypes (luminal, HER2, Triple negative). Start with Triple negatives.
125 cases Breast tumour and metastatic lymph nodes in breast cancer cases with outcomes of metastasis to lung or bone.
100 cases of rare tumours - fibrolamellar hepatocellular carcinoma. FFPE, frozen, BC.
200 cases of FFPE tissue sections from breast, lung adenocarcinoma, and lung squamous cell carcinoma with matching normal tissue (only pathology data requested).