NOSi, Canada

Registration Status: Completed

Objective: The purpose of this study is to determine if Nitric Oxide Sinus irrigation (NOSi) rinse is effective as a treatment for Biofilm-Associated Recalcitrant Chronic Rhinosinusitis as compared to a standard of care control. Collection of samples for biomarker research is also part of this study.Samples will be stored and analysis will be performed on biomarker variants thought to play a role in sinusitis including, but not limited to, specific candidate genes/genome-wide analysis for RNA, serum analytes, or tissue biomarkers to evaluate their association with observed clinical responses to NOSi. This blood may be used for further cytokine/chemokine evaluation, if needed to determine safety, of the Investigational Medicinal Product (IMP)

Registered Biobank Name NOSi
Biobank Leader Athenea Pascual
Country Canada
Email for biobank inquiries
Principal Investigator Amin Javer
User Type
  • Mono: A biobank that supports a specific research project, may have few staff members, a small-scale accrual scope with little to no initial intention of releasing or distributing biospecimens to secondary parties
  • Oligo: A biobank that supports several research groups or clinical trials, may or may not be designed to release biospecimens outside their collaborative group
  • Poly: A biobank that has generally a larger accrual scope, resources, and multiple users outside the biobank proper
Biospecimen Collected: