UNB Saint John-DMNB Biobank: Analysis of biospecimens and clinical data from cancer patients and volunteers without cancer, Canada

Certification Status: Approved

Registration Status: Completed

Objective: Reiman Biobank was established in 2013, at the DMNB Open Concept Lab, Dept. of Biology, University of New Brunswick, Saint John. The bank is led by the Clinical Investigator Dr. Tony Reiman and the Senior Scientist, Dr. Alli Murugesan in coordination with other Clinical Investigators, Research Scientist, Research Technicians, Postdoctoral Fellows and Graduate Students of the Reiman Cancer Research Lab. Banked samples include Cancer Patients/Healthy volunteers/Anonymized non-cancer patients Specimens- Blood and bone marrow samples processed to isolate plasma, WBC, MNC; immunomagnet-based separation of plasma cells (CD138 positive) etc for research purposes. All biobank procedures are carried out in accordance to Horizon Health Network and UNB Research Ethics Boards, Dalhousie University and UNB Biosafety Committees.

Registered Biobank Name	UNB Saint John-DMNB Biobank: Analysis of biospecimens and clinical data from cancer patients and volunteers without cancer
Biobank Leader	Dr. Aimee Wong
Country	Canada
Email for biobank inquiries	aimee.wong@unb.ca
Principal Investigator	Dr. Anthony Reiman
Website
User Type Mono: A biobank that supports a specific research project, may have few staff members, a small-scale accrual scope with little to no initial intention of releasing or distributing biospecimens to secondary parties Oligo: A biobank that supports several research groups or clinical trials, may or may not be designed to release biospecimens outside their collaborative group Poly: A biobank that has generally a larger accrual scope, resources, and multiple users outside the biobank proper	Poly - Collection aimed at supporting undetermined, multiple users with ethics approved research projects, through a defined access/application mechanism.

Biospecimen Collected:

Cohort Highlights

100 cases Next Generation Sequencing assay to detect all classes of genetic variant in Lung Cancer using a single Diagnostic test.
200 cases Colorectal TMA for QC purposes in support of study of tumor infiltrating lymphocytes in ovarian cancer tissues.
Build 300 cases breast cancer TMA containing primary tumour and matched metastatic LN for various subtypes (luminal, HER2, Triple negative). Start with Triple negatives.
125 cases Breast tumour and metastatic lymph nodes in breast cancer cases with outcomes of metastasis to lung or bone.
100 cases of rare tumours - fibrolamellar hepatocellular carcinoma. FFPE, frozen, BC.
200 cases of FFPE tissue sections from breast, lung adenocarcinoma, and lung squamous cell carcinoma with matching normal tissue (only pathology data requested).