Neurogenetics, Canada

Registration Status: Completed

Objective: The Neurogenetics Tissue Biobank at the Hotchkiss Brain Institute under University of Calgary was generated to support and knowledge translation in child and youth mental illness and on developing a world-class program of research that will contribute to prediction, prevention, and early intervention in these diseases. Special focus on three major areas: i. Population Neurogenetics and Precision Medicine ii. Autism Spectrum Project: Harnessing the Power of Population-Based Samples for Gene x Environment iii. International OCD Consortium, Neuroimaging, and OCD for the Child and adolescent. Our Biobank currently supports various projects at Alberta, Ontario, Quebec and Michigan (US) areas.

Registered Biobank Name	Neurogenetics
Biobank Leader	S-M Shaheen
Country	Canada
Email for biobank inquiries	shaheen70@gmail.com
Principal Investigator	Dr. Paul Arnold
Website
User Type Mono: A biobank that supports a specific research project, may have few staff members, a small-scale accrual scope with little to no initial intention of releasing or distributing biospecimens to secondary parties Oligo: A biobank that supports several research groups or clinical trials, may or may not be designed to release biospecimens outside their collaborative group Poly: A biobank that has generally a larger accrual scope, resources, and multiple users outside the biobank proper

Biospecimen Collected:

Cohort Highlights

100 cases Next Generation Sequencing assay to detect all classes of genetic variant in Lung Cancer using a single Diagnostic test.
200 cases Colorectal TMA for QC purposes in support of study of tumor infiltrating lymphocytes in ovarian cancer tissues.
Build 300 cases breast cancer TMA containing primary tumour and matched metastatic LN for various subtypes (luminal, HER2, Triple negative). Start with Triple negatives.
125 cases Breast tumour and metastatic lymph nodes in breast cancer cases with outcomes of metastasis to lung or bone.
100 cases of rare tumours - fibrolamellar hepatocellular carcinoma. FFPE, frozen, BC.
200 cases of FFPE tissue sections from breast, lung adenocarcinoma, and lung squamous cell carcinoma with matching normal tissue (only pathology data requested).