The Canadian Microbiome Vault, Canada

Registration Status: Completed

Objective: CMV is a repository of living human microbiomes available for basic and preclinical research. The goal of the CMV is to collect, preserve and provide access to microbiomes representative of the Canadian diversity in health and diseases, to rare microbiomes that are at risk of disappearing and to time-sensitive microbiomes that can only be collected transitorily due to epidemic and pandemic.

Registered Biobank Name	The Canadian Microbiome Vault
Biobank Leader	Daniel Figeys
Country	Canada
Email for biobank inquiries	dfigeys@uottawa.ca
Principal Investigator	Daniel Figeys, Alain Stintzi, Jean-Francois Couture
Website
User Type Mono: A biobank that supports a specific research project, may have few staff members, a small-scale accrual scope with little to no initial intention of releasing or distributing biospecimens to secondary parties Oligo: A biobank that supports several research groups or clinical trials, may or may not be designed to release biospecimens outside their collaborative group Poly: A biobank that has generally a larger accrual scope, resources, and multiple users outside the biobank proper

Biospecimen Collected:

Cohort Highlights

100 cases Next Generation Sequencing assay to detect all classes of genetic variant in Lung Cancer using a single Diagnostic test.
200 cases Colorectal TMA for QC purposes in support of study of tumor infiltrating lymphocytes in ovarian cancer tissues.
Build 300 cases breast cancer TMA containing primary tumour and matched metastatic LN for various subtypes (luminal, HER2, Triple negative). Start with Triple negatives.
125 cases Breast tumour and metastatic lymph nodes in breast cancer cases with outcomes of metastasis to lung or bone.
100 cases of rare tumours - fibrolamellar hepatocellular carcinoma. FFPE, frozen, BC.
200 cases of FFPE tissue sections from breast, lung adenocarcinoma, and lung squamous cell carcinoma with matching normal tissue (only pathology data requested).