Specimen Collection in Gynecologic Cancer, Canada

Registration Status: Completed

Objective: The purpose is to gather blood and unused tissue samples (either normal, malignant, or both), which will be removed at the time of surgery, and will be stored for future use in cancer research. From tissue samples we will extract DNA/RNA and cell lines to look for new biomarkers that can help future cancer treatment. The long term goal is to perform research in order to contribute information in the fight against cancer i.e., to develop better therapies for cancer. The short term goal is to collect human blood and tissue samples for use in future research studies on cancer.

Registered Biobank Name	Specimen Collection in Gynecologic Cancer
Biobank Leader	maroua mbarik
Country	Canada
Email for biobank inquiries	Maroua.mbarik@ladydavis.ca
Principal Investigator	Walter Gotlieb
Website
User Type Mono: A biobank that supports a specific research project, may have few staff members, a small-scale accrual scope with little to no initial intention of releasing or distributing biospecimens to secondary parties Oligo: A biobank that supports several research groups or clinical trials, may or may not be designed to release biospecimens outside their collaborative group Poly: A biobank that has generally a larger accrual scope, resources, and multiple users outside the biobank proper

Biospecimen Collected:

Cohort Highlights

100 cases Next Generation Sequencing assay to detect all classes of genetic variant in Lung Cancer using a single Diagnostic test.
200 cases Colorectal TMA for QC purposes in support of study of tumor infiltrating lymphocytes in ovarian cancer tissues.
Build 300 cases breast cancer TMA containing primary tumour and matched metastatic LN for various subtypes (luminal, HER2, Triple negative). Start with Triple negatives.
125 cases Breast tumour and metastatic lymph nodes in breast cancer cases with outcomes of metastasis to lung or bone.
100 cases of rare tumours - fibrolamellar hepatocellular carcinoma. FFPE, frozen, BC.
200 cases of FFPE tissue sections from breast, lung adenocarcinoma, and lung squamous cell carcinoma with matching normal tissue (only pathology data requested).