DNA Biobank "Miras", Kazakhstan

Registration Status: Pending

Objective: The aim of biobank is to identify genetic markers and improve prevention, diagnosis and treatment of life-threatening illnesses â€“ including heart diseases, stroke, diabetes, depression, pregnancy complications and etc. Â«MirasÂ» Biobank was established in the frame of EC 7th FP Â«Genetic studies of pre-eclampsia (PE) in Central Asian and European populationsÂ» 2012-2016 â„–282540.

Registered Biobank Name	DNA Biobank "Miras"
Biobank Leader	Gulnara Svyatova
Country	Kazakhstan
Email for biobank inquiries	respmgk@mail.ru
Principal Investigator	Gulnara Svyatova
Website	http://biobankdna.com/
User Type Mono: A biobank that supports a specific research project, may have few staff members, a small-scale accrual scope with little to no initial intention of releasing or distributing biospecimens to secondary parties Oligo: A biobank that supports several research groups or clinical trials, may or may not be designed to release biospecimens outside their collaborative group Poly: A biobank that has generally a larger accrual scope, resources, and multiple users outside the biobank proper	Oligo - Collection aimed at supporting several research projects, a research group or a research consortium

Biospecimen Collected:

Cohort Highlights

100 cases Next Generation Sequencing assay to detect all classes of genetic variant in Lung Cancer using a single Diagnostic test.
200 cases Colorectal TMA for QC purposes in support of study of tumor infiltrating lymphocytes in ovarian cancer tissues.
Build 300 cases breast cancer TMA containing primary tumour and matched metastatic LN for various subtypes (luminal, HER2, Triple negative). Start with Triple negatives.
125 cases Breast tumour and metastatic lymph nodes in breast cancer cases with outcomes of metastasis to lung or bone.
100 cases of rare tumours - fibrolamellar hepatocellular carcinoma. FFPE, frozen, BC.
200 cases of FFPE tissue sections from breast, lung adenocarcinoma, and lung squamous cell carcinoma with matching normal tissue (only pathology data requested).