Banque dechantillons biologiques et de donnees (cliniques et biologiques) en transplantation renale, Canada

Certification Status: Complete Education

Registration Status: Completed

Objective: The research which will be conducted with the banked samples will aim to identify biomarkers, from blood, urine and tissues (renal or blood cells) in kidney donors and transplanted recipients, that could predict the risk of acute or chronic rejection of each person with more precision. The results of the research could help us better understand how to predict and treat acute and chronic renal transplant rejection.

Registered Biobank Name	Banque dechantillons biologiques et de donnees (cliniques et biologiques) en transplantation renale
Biobank Leader	Julie Turgeon
Country	Canada
Email for biobank inquiries	julie.turgeon.chum@ssss.gouv.qc.ca
Principal Investigator	Heloise Cardinal
Website
User Type Mono: A biobank that supports a specific research project, may have few staff members, a small-scale accrual scope with little to no initial intention of releasing or distributing biospecimens to secondary parties Oligo: A biobank that supports several research groups or clinical trials, may or may not be designed to release biospecimens outside their collaborative group Poly: A biobank that has generally a larger accrual scope, resources, and multiple users outside the biobank proper	Poly - Collection aimed at supporting undetermined, multiple users with ethics approved research projects, through a defined access/application mechanism.

Biospecimen Collected:

Cohort Highlights

100 cases Next Generation Sequencing assay to detect all classes of genetic variant in Lung Cancer using a single Diagnostic test.
200 cases Colorectal TMA for QC purposes in support of study of tumor infiltrating lymphocytes in ovarian cancer tissues.
Build 300 cases breast cancer TMA containing primary tumour and matched metastatic LN for various subtypes (luminal, HER2, Triple negative). Start with Triple negatives.
125 cases Breast tumour and metastatic lymph nodes in breast cancer cases with outcomes of metastasis to lung or bone.
100 cases of rare tumours - fibrolamellar hepatocellular carcinoma. FFPE, frozen, BC.
200 cases of FFPE tissue sections from breast, lung adenocarcinoma, and lung squamous cell carcinoma with matching normal tissue (only pathology data requested).