CU-Med Biobank, Hong Kong

Certification Status: Approved

Registration Status: Completed

Objective: A Biobank or biorepository is a laboratory that accepts, processes, stores and distributes biospecimens and the associated data for basic and clinical researches. The incident rate of diseases, especially cancer is raising over years and it becomes a major threat of human health. To develop better treatment of diseases and to improve patient survival, in-depth studies of the genetic and molecular mechanisms of diseases were essential. These more accurate and comprehensive studies require high-quality human biological samples, such as tumor tissues, patient blood, and body fluids. By using these biological samples, researchers can explore the disease mechanisms from genomics, transcriptome and proteome levels. They can also validate their research results in real patient samples. These findings will contribute to improve prevention, enhance diagnosis, develop new treatment and eventually cure of diseases. For these reasons, we plan to establish a standardized, accredited Biobank for standardized and systematic collection, storage and application of patient biological samples. This system will provide researchers with high-quality biological samples and comprehensive clinical, pathological including molecular/genetic information for their research. Therefore, a standardized and accredited Biobank, is a pivotal bridge to improve the translation of basic research into clinical applications.

Registered Biobank Name	CU-Med Biobank
Biobank Leader	Dr. Terry Cho Tsun OR
Country	Hong Kong
Email for biobank inquiries	terryor@cuhk.edu.hk
Principal Investigator	Prof. Ronald CW Ma and Prof. KF To
Website
User Type Mono: A biobank that supports a specific research project, may have few staff members, a small-scale accrual scope with little to no initial intention of releasing or distributing biospecimens to secondary parties Oligo: A biobank that supports several research groups or clinical trials, may or may not be designed to release biospecimens outside their collaborative group Poly: A biobank that has generally a larger accrual scope, resources, and multiple users outside the biobank proper	Poly - Collection aimed at supporting undetermined, multiple users with ethics approved research projects, through a defined access/application mechanism.

Biospecimen Collected:

Cohort Highlights

100 cases Next Generation Sequencing assay to detect all classes of genetic variant in Lung Cancer using a single Diagnostic test.
200 cases Colorectal TMA for QC purposes in support of study of tumor infiltrating lymphocytes in ovarian cancer tissues.
Build 300 cases breast cancer TMA containing primary tumour and matched metastatic LN for various subtypes (luminal, HER2, Triple negative). Start with Triple negatives.
125 cases Breast tumour and metastatic lymph nodes in breast cancer cases with outcomes of metastasis to lung or bone.
100 cases of rare tumours - fibrolamellar hepatocellular carcinoma. FFPE, frozen, BC.
200 cases of FFPE tissue sections from breast, lung adenocarcinoma, and lung squamous cell carcinoma with matching normal tissue (only pathology data requested).