Banque de donnees et de materiel biologique en sarcome du CIUSSS de l'Est-de-l'Ile-de-Montreal, Canada

Certification Status: Complete Education

Registration Status: Completed

Objective: The purpose this bank is to create a platform to equip researchers with methodological tools. These tools will stimulate research, innovation, cohesion and visibility for musculoskeletal tumors. It will provide research teams with biological material (blood, tissue, fluid, etc.) as well as with clinical data associated with biological material for their studies. The studies carried out on biological material and associated data could generate new data that could in turn be entered into the bank. The bank aims to collect medical data and biological material from patients diagnosed with sarcoma or related tumors. The bank will enable the cross-use of clinical data with participants' biological material for the following purposes: a) Provide researchers with the tools to understand the causes and mechanisms that characterize sarcomas. b) Develop structural resources for sarcoma research. c) Foster collaboration between researchers d) Promote the development of sarcoma research projects e) Reduce the time needed between hypothesis generation and experimental validation. f) Promote optmization of participants' data and biological material g) Reduce over-solicitation of participants.

Registered Biobank Name	Banque de donnees et de materiel biologique en sarcome du CIUSSS de l'Est-de-l'Ile-de-Montreal
Biobank Leader	Janie Barry
Country	Canada
Email for biobank inquiries	jbarry.hmr@ssss.gouv.qc.ca
Principal Investigator	Dr Jonathan Noujaim
Website
User Type Mono: A biobank that supports a specific research project, may have few staff members, a small-scale accrual scope with little to no initial intention of releasing or distributing biospecimens to secondary parties Oligo: A biobank that supports several research groups or clinical trials, may or may not be designed to release biospecimens outside their collaborative group Poly: A biobank that has generally a larger accrual scope, resources, and multiple users outside the biobank proper	Poly - Collection aimed at supporting undetermined, multiple users with ethics approved research projects, through a defined access/application mechanism.

Biospecimen Collected:

Cohort Highlights

100 cases Next Generation Sequencing assay to detect all classes of genetic variant in Lung Cancer using a single Diagnostic test.
200 cases Colorectal TMA for QC purposes in support of study of tumor infiltrating lymphocytes in ovarian cancer tissues.
Build 300 cases breast cancer TMA containing primary tumour and matched metastatic LN for various subtypes (luminal, HER2, Triple negative). Start with Triple negatives.
125 cases Breast tumour and metastatic lymph nodes in breast cancer cases with outcomes of metastasis to lung or bone.
100 cases of rare tumours - fibrolamellar hepatocellular carcinoma. FFPE, frozen, BC.
200 cases of FFPE tissue sections from breast, lung adenocarcinoma, and lung squamous cell carcinoma with matching normal tissue (only pathology data requested).