Sports Cardiology BC: The Effects of Cardiovascular Disease on Sports and Exercise Outcomes Study (SPORTS-CVD), Canada

Registration Status: Completed

Objective: The SPORTS-CVD data registry and biobank will integrate clinical, biomarker, and lifestyle data to investigate novel biomarkers of cardiac disease and dysfunction, risk factors for adverse cardiovascular events, evaluate diagnostic methods, study responses to novel interventions, and monitor patient outcomes.

Registered Biobank Name	Sports Cardiology BC: The Effects of Cardiovascular Disease on Sports and Exercise Outcomes Study (SPORTS-CVD)
Biobank Leader	Reid Mitchell
Country	Canada
Email for biobank inquiries	reid.mitchell@vch.ca
Principal Investigator	Saul Isserow, Nathaniel Moulson, James McKinney
Website
User Type Mono: A biobank that supports a specific research project, may have few staff members, a small-scale accrual scope with little to no initial intention of releasing or distributing biospecimens to secondary parties Oligo: A biobank that supports several research groups or clinical trials, may or may not be designed to release biospecimens outside their collaborative group Poly: A biobank that has generally a larger accrual scope, resources, and multiple users outside the biobank proper

Biospecimen Collected:

Cohort Highlights

100 cases Next Generation Sequencing assay to detect all classes of genetic variant in Lung Cancer using a single Diagnostic test.
200 cases Colorectal TMA for QC purposes in support of study of tumor infiltrating lymphocytes in ovarian cancer tissues.
Build 300 cases breast cancer TMA containing primary tumour and matched metastatic LN for various subtypes (luminal, HER2, Triple negative). Start with Triple negatives.
125 cases Breast tumour and metastatic lymph nodes in breast cancer cases with outcomes of metastasis to lung or bone.
100 cases of rare tumours - fibrolamellar hepatocellular carcinoma. FFPE, frozen, BC.
200 cases of FFPE tissue sections from breast, lung adenocarcinoma, and lung squamous cell carcinoma with matching normal tissue (only pathology data requested).