PHIL LIVER Biobank, Philippines

Certification Status: Invite Member

Registration Status: Completed

Objective: The PHIL LIVER Biobank project, implemented by the University of the Philippines Manila–National Institutes of Health (UPM-NIH) and led by Dr. Janus P. Ong, seeks to establish a functional biorepository to support interdisciplinary research on liver health and diseases in the Philippines. Recognizing the country’s high burden of liver disease, particularly from hepatitis B and hepatocellular carcinoma, the project aims to provide high-quality, clinically annotated specimens essential for advancing translational research. It forms part of the broader UPM-NIH Liver Research Program, which will serve as the foundation for a future Center for Liver Research and the central hub of the Philippine Liver Research Network. The biobank will house a comprehensive electronic disease registry and systematically collected biospecimens to support local and international studies, standardize research practices, and enable more efficient, collaborative, and impactful liver disease research that contributes to improved health outcomes for Filipinos.

Registered Biobank Name	PHIL LIVER Biobank
Biobank Leader	Dr. Janus P. Ong
Country	Philippines
Email for biobank inquiries	jpong@up.edu.ph
Principal Investigator	Dr. Janus P. Ong
Website
User Type Mono: A biobank that supports a specific research project, may have few staff members, a small-scale accrual scope with little to no initial intention of releasing or distributing biospecimens to secondary parties Oligo: A biobank that supports several research groups or clinical trials, may or may not be designed to release biospecimens outside their collaborative group Poly: A biobank that has generally a larger accrual scope, resources, and multiple users outside the biobank proper	Oligo - Collection aimed at supporting several research projects, a research group or a research consortium

Biospecimen Collected:

Cohort Highlights

100 cases Next Generation Sequencing assay to detect all classes of genetic variant in Lung Cancer using a single Diagnostic test.
200 cases Colorectal TMA for QC purposes in support of study of tumor infiltrating lymphocytes in ovarian cancer tissues.
Build 300 cases breast cancer TMA containing primary tumour and matched metastatic LN for various subtypes (luminal, HER2, Triple negative). Start with Triple negatives.
125 cases Breast tumour and metastatic lymph nodes in breast cancer cases with outcomes of metastasis to lung or bone.
100 cases of rare tumours - fibrolamellar hepatocellular carcinoma. FFPE, frozen, BC.
200 cases of FFPE tissue sections from breast, lung adenocarcinoma, and lung squamous cell carcinoma with matching normal tissue (only pathology data requested).