Hospital for Endocrine Surgery Research Center Biobank, United States

Registration Status: Completed

Objective: The Hospital for Endocrine Surgery research Center (HESRC) Biobank is a prospective, hospital-based biorepository established at the Hospital for Endocrine Surgery (Tampa, Florida, USA) to support genetic, molecular, and translational research on endocrine tumors and related conditions. It systematically collects and stores high-quality biological specimens — including tumor tissue, adjacent normal tissue, serum, plasma, urine, lymph, and germline DNA (from blood and/or saliva) — together with richly annotated longitudinal clinical data from patients undergoing surgery for thyroid, parathyroid, and adrenal tumors or associated endocrine disorders. Samples are obtained during clinically indicated procedures (with excess tissue used post-diagnosis) or via minimally invasive research collections coordinated with routine care. All materials are de-identified, assigned unique codes, and stored indefinitely in a secure, encrypted system (eLabNext) under strict confidentiality and HIPAA-compliant protocols. Primary aims include enabling next-generation sequencing (NGS), whole-exome sequencing, transcriptomics, epigenomics, proteomics, and functional studies to identify somatic/germline mutations, molecular pathways, biomarkers for early detection/prognosis/therapy, gene-environment interactions, and pharmacogenomic predictors of treatment response and recurrence. The repository supports future hypothesis-driven projects, with annual accrual targets of up to 3,000 participants and collection from ≥80% of eligible surgical cases. The biobank operates under WCG IRB approval, follows Common Rule and Belmont Report principles, obtaining explicit informed consent from adult participants only.

Registered Biobank Name Hospital for Endocrine Surgery Research Center Biobank
Biobank Leader Fabio Faucz
Country United States
Email for biobank inquiries fabio.faucz@hcahelthcare.com
Principal Investigator Fabio Faucz
Website
User Type
  • Mono: A biobank that supports a specific research project, may have few staff members, a small-scale accrual scope with little to no initial intention of releasing or distributing biospecimens to secondary parties
  • Oligo: A biobank that supports several research groups or clinical trials, may or may not be designed to release biospecimens outside their collaborative group
  • Poly: A biobank that has generally a larger accrual scope, resources, and multiple users outside the biobank proper
Biospecimen Collected:
Cohort Highlights